Pizza RestaurantClemson, SC

Domino's – Clemson, SC

Open now · closes 12:00 AM

Directions Call

Illustrative photo

Opening hours

Open now · closes 12:00 AM

Weekly opening hours of Domino's
Monday	10:30 AM – 12:00 AM
Tuesday	10:30 AM – 12:00 AM
Wednesday	10:30 AM – 12:00 AM
Thursday	10:30 AM – 12:00 AM
Friday	10:30 AM – 2:00 AM
Saturday	10:30 AM – 2:00 AM
Sunday	10:30 AM – 12:00 AM

Local time in Clemson: 2:09 PM (EDT). Holiday hours may differ – call (864) 653-7575 to confirm.

Location & directions

Tap for directions

501 Old Greenville Highway
Clemson, SC 29631

Google Maps Apple Maps Waze

About Domino's

Domino's is a pizza restaurant you'll find at 501 Old Greenville Highway in Clemson, South Carolina. Our Clemson guide covers 72 food and drink spots, and this is one of them.

Domino's is open 7 days a week, usually 10:30 AM – 12:00 AM. It stays open late, until 12:00 AM on most nights.

Service options include takeout.

You can reach the team at (864) 653-7575.

Quick facts

Category: Pizza Restaurant
Address: 501 Old Greenville Highway, Clemson, SC 29631
Phone: (864) 653-7575
Hours: Open 7 days a week, usually 10:30 AM – 12:00 AM
Listing updated: September 2026 · Suggest an edit

Popular times (estimated)

6AM

9AM

12PM

3PM

6PM

9PM

Estimated from typical visit patterns for pizza restaurants and this venue’s opening hours – not live data.

Features & amenities

Service options

Takeout

Reviews

Write a review

No visitor reviews yet. Been to Domino's? Share your experience to help other diners.

Frequently asked questions

What are Domino's's opening hours?

Open 7 days a week, usually 10:30 AM – 12:00 AM. Monday: 10:30 AM – 12:00 AM; Tuesday: 10:30 AM – 12:00 AM; Wednesday: 10:30 AM – 12:00 AM; Thursday: 10:30 AM – 12:00 AM; Friday: 10:30 AM – 2:00 AM; Saturday: 10:30 AM – 2:00 AM; Sunday: 10:30 AM – 12:00 AM.

Is Domino's open on Sunday?

Yes, Domino's is open on Sundays: 10:30 AM – 12:00 AM.

Where is Domino's located?

Domino's is located at 501 Old Greenville Highway, Clemson, SC 29631.

What is the phone number of Domino's?

You can call Domino's at (864) 653-7575.

Does Domino's offer delivery or takeout?

Delivery is not listed for Domino's, and takeout is available. Listed service options: takeout.